Prothrombin Monoclonal Antibody (C19), Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Prothrombin
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Alias
Activation peptide fragment 1, Activation peptide fragment 2, bovine prothrombin protein, Cf2, Cf-2, coagulation factor 2, coagulation factor II, coagulation factor II (thrombin), coagulation factor II [thrombin], coagulation factor II, thrombin, F2, FII, kringle-2 domain, fragment-2, prepro-coagulation factor II, preprothrombin, prothrombin, prothrombin B-chain, prothrombin precursor, PT, RPRGL2, serine protease, THPH1, THROMBIN, Thrombin heavy chain, Thrombin light chain
Gene Symbols
F2
Isotype
IgG2b κ
Purification Method
Protein A/G
Gene
F2
Clone
C19
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Rat
Gene Accession No.
P18292
Gene ID (Entrez)
29251
Immunogen
Recombinant Rat F2 protein, Ser201-Arg323 (Accession #P18292)
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
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Description
- Prothrombin or Coagulation factor II, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which μgtimately results in the stemming of blood loss
- F2 also plays a role in maintaining vascular integrity during development and postnatal life
- Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.