KLRG1 Monoclonal Antibody (2F1), Brilliant Ultra Violet™ 615, eBioscience™, Invitrogen™
Syrian Hamster Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
KLRG1
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias
2F1, 2F1-Ag, CLEC15A, C-type lectin domain family 15 member A, C-type lectin domain family 15, member A, ITIM-containing receptor MAFA-L, killer cell lectin like receptor G1, killer cell lectin-like receptor subfamily G member 1, killer cell lectin-like receptor subfamily G, member 1, Klrg1, Mafa, MAFA-2F1, MAFAL, MAFA-L, MAFA-LIKE, MAFA-like receptor, Mast cell function-associated antigen, mast cell function-associated antigen (ITIM-containing), mast cell function-associated antigen 2F1, natural killer cell receptor
Gene Symbols
Klrg1
Primary or Secondary
Primary
Content And Storage
4°, C, store in dark, DO NOT FREEZE!
Clone
2F1
Applications
Flow Cytometry
Conjugate
Brilliant Ultraviolet 615
Host Species
Syrian Hamster
Target Species
Mouse
Gene Accession No.
O88713
Gene ID (Entrez)
50928
Isotype
IgG
Purification Method
Affinity chromatography
Gene
Klrg1
Related Products
Description
- KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains
- These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1
- KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells
- NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.