38-540-0

SMAD1 Polyclonal Antibody, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 38-540-0-Each-of-1 In Stock ₹ 40,050.00

38-540-0 - Each of 1

₹ 40,050.00

In Stock

Quantity

1

Base Price: ₹ 40,050.00

GST (18%): ₹ 7,209.00

Total Price: ₹ 47,259.00

Antigen

SMAD1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SMAD1

Gene Alias

AI528653; BSP1; BSP-1; dwarfin-A; Dwf-A; DWFC; hSMAD1; JV41; JV4-1; JV5-1; MAD (mothers against decapentaplegic, Drosophila) homolog 1; MAD homolog 1; MAD homolog1 (mothers against decapentaplegic, Drosophila); MAD, mothers against decapentaplegic homolog 1; Madh1; MADH5; MADR1; Mad-related protein 1; Mlp1; mMad1; mothers against decapentaplegic homolog 1; mothers against DPP homolog 1; mothers-against-DPP-related 1; Mothers-against-DPP-related-1; MusMLP; OTTHUMP00000220456; SMAD; Smad 1; SMAD family member 1; SMAD, mothers against DPP homolog 1; Smad1; SMAD5; TGF-beta signaling protein 1; transforming growth factor-beta signaling protein 1; Transforming growth factor-beta-signaling protein 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17125, 4086

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.25 mg/mL

Formulation

PBS with 0.1% sodium azide; pH 7.4

Gene Accession No.

P70340, Q15797

Gene Symbols

SMAD1

Immunogen

Synthetic peptide derived from an internal region of the human Smad1 protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate

Product Type

Antibody

Isotype

IgG

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Description

  • The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C
  • elegans gene Sma
  • SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways
  • This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses
  • In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase
  • The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation
  • This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation
  • Alternatively spliced transcript variants encoding the same protein have been observed.