3843962

CD8 Mouse anti-Human, Alexa Fluor 488, Clone: RPA-T8, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD8

Applications

Flow Cytometry

Conjugate

Alexa Fluor 488

Regulatory Status

RUO

Target Species

Baboon, Cynomolgus, Human, Rhesus Monkey

Immunogen

Human CD8a

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Clone

RPA-T8

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Immunology

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Description

CD8α; CD8A; CD8 alpha; Leu2; MAL; T8; p32

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Description

  • Clone RPA-T8 reacts with the α subunit (32kDa) of the two-chain complex expressed on T-cytoxic/suppressor cell populations
  • CD8 molecule binds to HLA class I molecules during interaction of CD8+ T cells with antigen-presenting cells or with target cells
  • RPA-T8 reacts with approximately 13-48% of peripheral blood lymphocytes and 80% of thymocytes, as well as a subset of NK cells
  • RPA-T8 and HIT8a (Mfr
  • No.555337) are not cross-blocking
  • Host Species: Mouse Clone: RPA-T8 Isotype: IgG1, κ Cross Reactivity: Human Flow Cytometry