3844488
CD19 Mouse anti-Human, Alexa Fluor 700, Clone: HIB19, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD19
Concentration
0.2mg/mL
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Isotype
IgG1 κ
Purification Method
Affinity Purified
Clone
HIB19
Applications
Flow Cytometry
Conjugate
Alexa Fluor 700
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Description
- Reacts with the 95kDa type I transmembrane glycoprotein expressed during all stages of B-cell differentiation and maturation, except on plasma cells
- CD19 is also present on follicular dendritic cells
- It is not found on T cells or on normal granulocytes
- CD19 plays a role in regulation of B-cell proliferation
- It associates with the complement receptor 2 (CD21), TAPA-1 (CD81), Leu 13, and/or MHC class II to form a signal transduction complex on the surface of B cells
- Anti-CD19 clone HIB19 partially blocks clone B43, another CD19 mAb
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
- Host Species: Mouse Clone: HIB19 Isotype: IgG1, κ Cross Reactivity: Human Flow Cytometry