3844454
CD194 Mouse anti-Human, PE-Cy7, Clone: 1G1, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD194
Concentration
0.2mg/mL
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Immunogen
Human CCR4 Transfected Cell Line
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
1G1
Applications
Flow Cytometry
Conjugate
PE-Cyanine7
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Description
CCR4; C-C chemokine receptor type 4; CMKBR4; K5-5
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Description
- The monoclonal antibody 1G1 reacts with the human CC chemokine receptor, CCR4
- CCR4 (previously known as K5-5), a seven-transmembrane, G-protein-coupled receptor, is the specific receptor for CC chemokines, MDC/CCL22 and TARC/CC17
- It has been shown that CCR4 mRNA is expressed mainly in thymus and spleen
- CCR4 mRNA was also detected in peripheral T-lymphocytes, basophils, monocytes and platelets
- In addition, CCR4 has been shown to be expressed selectively on polarized Th2 cells
- The human CCR4 gene has been mapped to chromosome 3p24
- The immunogen used to generate 1G1 hybridoma was human CCR4-transfected L1.2 mouse lymphoma cells
- This antibody is NOT a neutralizing antibody
- Host Species: Mouse Clone: 1G1 Isotype: IgG1 κ Species Reactivity: Human Immunogen: Human CCR4-Transfected L1.2 Mouse Lymphoma Flow Cytometry, Immunofluorescence