3853535
CD11c Mouse anti-Human, APC, Clone: B-LY6, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD11c
Classification
Monoclonal
Host Species
Mouse
Target Species
Human
Immunogen
Spleen Cells from Human with Hairy Cell Leukemia
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Conjugate
APC
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Description
ITGAX; AlphaX integrin chain; Axb2; Integrin alpha-X; CR4; Leu M5; SLEB6
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Description
- Reacts with the 150kDa adhesion glycoprotein (p150, integrin α chain) expressed on NK cells, a subset of B and T cells, monocytes, granulocytes and macrophages
- It associates with CD18 to form the CD11c/CD18 complex, which binds fibrinogen and has been reported to be a receptor for iC3b and ICAM-1
- Reports indicate that CD11c/CD18 may play a role as an adhesion molecule which binds to receptors on stimulated epithelium
- This antibody is routinely tested by flow cytometric analysis
- Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature
- Flow Cytometry