3969407
CD3 Mouse anti-Human, APC-H7, Clone: SK7, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD3
Applications
Flow Cytometry
Conjugate
APC-H7
Regulatory Status
RUO
Target Species
Human
Immunogen
Human Thymocytes
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
SK7
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Immunology
Formulation
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Isotype
IgG1 κ
Purification Method
Affinity Purified
Description
CD3-epsilon; CD3E; Leu4; T-cell surface antigen T3/Leu-4 epsilon chain; T3E
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Description
- CD3 reacts with ε chain of the CD3 antigen/T-cell antigen receptor (TCR) complex
- This complex is composed of at least six proteins that range in molecular weight from 20 to 30kDa
- The antigen recognized by CD3 antibodies is noncovalently associated with either α/β or γ/δ TCR (70 to 90kDa)
- The CD3 antigen is present on 61% to 85% of normal peripheral blood lymphocytes 60% to 85% of thymocytes and on Purkinje cells in cerebellum
- This antibody has a Mitogenic effect on most peripheral blood T lymphocytes, provided appropriate functional monocytes are present
- Host Species: Mouse Clone: SK7 Isotype: IgG1 κ Species Reactivity: Human Flow Cytometry