40-731-3100UL

MilliporeSigma™ anti-Integrin alphaIIb Clone: 283.16B7,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 40-731-3100UL-Each-of-1 In Stock ₹ 41,360.97

40-731-3100UL - Each of 1

₹ 41,360.97

In Stock

Quantity

1

Base Price: ₹ 41,360.97

GST (18%): ₹ 7,444.975

Total Price: ₹ 48,805.945

Antigen

Integrin αIIb

Classification

Monoclonal

Conjugate

Unconjugated

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Ascites

Applications

ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)

Clone

283.16B7

Formulation

Undiluted ascites.

Immunogen

integrin αIIbfrom M21-L-llb melanoma cells

Regulatory Status

RUO

Test Specificity

Recognizes the αIIbintegrin chain. Antibody Target Gene Symbol: ITGA2B Target Synonym: AI172977, ALPHA 2B, alphaIIb, CD41, CD41A, CD41B, GP2B, GPIIB, GTA, HPA3, INTEGRIN ALPHA 2B, Itga2b, LOC685269 Entrez Gene Name: integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

Content And Storage

−20°C

Isotype

IgG1

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Description

  • Specifically detects Integrin α IIb Clone: 283.16B7 in Human samples, and it is validated for ELISA, Flow Cytometry, Immunohistochemistry (Paraffin) The integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes
  • Integrins are heterodimers consisting of noncovalently associated α and β subunits
  • CD41 consists of two disulfide-linked subunits, GPIIba and GPIIbb
  • CD41 non-covalently associates with CD61 (integrin β3) and is expressed by megakaryocytes and platelets
  • The CD41/CD61 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.