4325926
CD3e Hamster anti-Mouse, V450, Clone: 500A2, BD
Hamster Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD3e
Concentration
0.2mg/mL
Classification
Monoclonal
Host Species
Hamster
Target Species
Mouse
Immunogen
Mouse T-cell receptor
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
500A2
Applications
Flow Cytometry
Conjugate
Violet Fluor 450 (V450)
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Isotype
IgG2 κ
Purification Method
Affinity Purified
Description
CD3ε chain
Related Products
Description
- This antibody has been reported to react with the 25-kDa ε chain of the T-cell receptor-associated CD3 complex expressed on thymocytes, mature T lymphocytes, and NK-T cells on many mouse stains
- Plate-bound and soluble hamster anti-mouse CD3e (clone 500A2) antibody has been reported to activate unprimed T cells in vitro
- Activation of a mouse T-cell clone by soluble hamster anti-mouse CD3e (clone 500A2) can be blocked by Fab fragments of anti-CD4 antibody GK1.5, suggesting that the hamster anti-mouse CD3e (clone 500A2) antibody may bind an epitope of CD3e close to a site at which CD4 associates with the T-cell receptor
- This hamster mAb to a mouse leukocyte antigen has been reported not to cross-react with rat leukocytes
- The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences
- It is excited by the 450 nm
- Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.