4537124
Epredia™ Lab Vision™ E-Cadherin Rabbit Monoclonal Antibody
Ensure accurate and reliable results in immunohistochemistry applications with Epredia™ Cadherin E, Rabbit Monoclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
E-Cadherin
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Regulatory Status
IVD
Immunogen
A synthetic peptide derived from the fifth cadherin domain of human cadherin
Clone
EP700Y
Classification
Monoclonal
Host Species
Rabbit
Research Discipline
Cancer and Tumor Biology
Primary or Secondary
Primary
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Description
- E-cadherin (uvomorulin, cell-CAM120/80) is a calcium-dependent cell adhesion molecule expressed predominantly in epithelial tissues
- It plays an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity
- Numerous studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis
- E-cadherin is used in distinguishing LCIS from DCIS and that of ILC from IDC in indeterminate cases
- Host Species: Rabbit Clone: EP700Y Species Reactivity: Human
- Others not known
- Immunogen: A synthetic peptide derived from the fifth cadherin domain of human cadherin Molecular Weight: 135/80kDa Positive Control: Breast Carcinoma Cellular Localization: Cell Membrane Recommended for: Immunohistochemistry (Formalin/paraffin)