4544036
Epredia™ Lab Vision™ Cytokeratin 5 Rabbit Monoclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ Cytokeratin 5, Rabbit Monoclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
Cytokeratin 5
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Regulatory Status
IVD
Immunogen
A synthetic peptide corresponding to residues on the C-term of human CK5
Clone
EP1601Y
Classification
Monoclonal
Host Species
Rabbit
Research Discipline
Cancer and Tumor Biology
Primary or Secondary
Primary
Related Products
Description
- Twenty human cytokeratins are divided into acidic (pI<5.7) and basic (pI>6.0) subfamilies
- Members of the acidic and basic subfamilies are found together in pairs
- The composition of cytokeratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state
- Many studies have shown the usefulness of cytokeratins as markers in cancer research and tumor identification
- Point mutations in cytokeratin-5 gene may cause Epidermolysis Bullosa Simplex and Dowling-Degos disease
- cytokeratin-5 is expressed in most epithelioid and biphasic mesotheliomas, thymoma, squamous and other carcinomas
- It is related to cytokeratin-6
- Host Species: Rabbit Clone: EP1601Y Isotype: IgG Species Reactivity: Human
- Others not known
- Immunogen: A synthetic peptide corresponding to residues on the C-terminus of human CK5 Molecular Weight: 59 kDa Positive Control: Mesothelioma Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin)