4544054

Epredia™ Lab Vision™ Cytokeratin, High Molecular Weight Ab-3, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry and immunofluorescence experiments.

Manufacturer: Fischer Scientific

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Antigen

Cytokeratin, High Molecular Weight Ab-3

Applications

Immunofluorescence, Immunohistochemistry (Paraffin)

Conjugate

Unconjugated

Regulatory Status

IVD

Immunogen

Solubilized keratin extracted from human stratum corneum

Clone

34BetaE12

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cytoskeletal Protein

Primary or Secondary

Primary

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Description

  • In normal cells, Ab-3 labels squamous, ductal and other complex epithelia
  • It reacts with benign small-acinir lesions of the prostate and does not react with hepatocytes, pancreatic acinar cells, proximal renal tubes or endometrial glands
  • In tumor cells, this antibody is reactive with both squamous and ductal neoplasms and variably with those derived from simple epithelium
  • Host Species: Mouse Clone: 34βE12 Isotype: IgG1 Species Reactivity: Human, Monkey, Horse and Rabbit
  • Others not known
  • Epitope: Not determined Immunogen: Solubilized keratin extracted from human stratum corneum Molecular Weight: 68 kDa (Cytokeratin 1), 58 kDa (Cytokeratin 5), 56.5 kDa (Cytokeratin 10) and 50 kDa (Cytokeratin 14) Positive Control: Squamous cell CA Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin) Immunofluorescence