4544650
Epredia™ Lab Vision™ CD3ε Rabbit Monoclonal Antibody
Obtain accurate and reproducible results in immunohistochemistry applications with Epredia™ CD3ε, Rabbit Monoclonal Antibody.
Manufacturer: Fischer Scientific
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Antigen
CD3e
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Regulatory Status
IVD
Immunogen
A synthetic peptide corresponding to residues in the cytoplasmic domain of human CD3epsilon. The antibody does not cross react with other subunits of CD3.
Clone
EP449E
Classification
Monoclonal
Host Species
Rabbit
Research Discipline
Cancer and Tumor Biology
Primary or Secondary
Primary
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Description
- CD3 consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta)
- The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR)
- It is involved in signal transduction to the T cell interior following antigen recognition
- CD3 antigen is a highly specific marker for T cells, and is present in the majority of T cell neoplasms
- Host Species: Rabbit Clone: EP449E Isotype: IgG Species Reactivity: Human
- Others not known
- Immunogen: A synthetic peptide corresponding to residues in the cytoplasmic domain of human CD3ε
- The antibody does not cross react with other subunits of CD3
- Molecular Weight: 23kDa Positive Control: Tonsil Cellular Localization: Membrane Recommended for: Immunohistochemistry (Formalin/paraffin)