4546369
GLUT-1 Rabbit Polyclonal Antibody, Epredia™
GLUT-1, Rabbit Polyclonal Ab is one marker in a comprehensive antibody portfolio that addresses all major disease states, ensuring the ideal tests are always available.
Manufacturer: Fischer Scientific
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Antigen
GLUT-1
Classification
Polyclonal
Host Species
Rabbit
Research Discipline
Steroids Hormones and Growth Factors
Immunogen
A synthetic peptide derived from C-terminal of human GLUT-1
Primary or Secondary
Primary
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Regulatory Status
IVD
Target Species
Human
Isotype
IgG
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Description
- Description Glucose is fundamental to the metabolism of mammalian cells
- Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF-1 induced signaling
- GLUT-1 is detectable in many human tissues including those of the colon, lung, stomach, esophagus, and breast
- GLUT-1 immunoreactivity in some cancers, including trans carcinoma of the urinary bladder, has been associated with aggressive behavior
- Host Species: Rabbit Isotype: IgG Species Reactivity: Human and Rat
- Others not tested
- Epitope: C-terminal Immunogen: A synthetic peptide derived from C-terminal of human GLUT-1 Molecular Weight: 55 kDa, 45 kDa depending on the extent of glycosylation Positive Control: Rat brain lysate; Breast CA, squamous cell CA, nonsmall-cell lung CA and esophageal CA Cellular Localization: Membrane and focal cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunofluorescence