4559174

Progesterone Receptor Ab-8 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ Progesterone Receptor Ab-8, Mouse Monoclonal Antibody.

Manufacturer: Fischer Scientific

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Antigen

Progesterone Receptor Ab-8

Applications

Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Regulatory Status

ASR, IVD

Immunogen

PgR from a human endometrial carcinoma (EnCa 101) grown in athymic mice

Clone

hPRa 2+hPRa 3

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cancer and Tumor Biology

Primary or Secondary

Primary

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Description

  • Human PgR exists in two forms: 116kDa (B-form) and 81kDa (A-form)
  • It acts as ligand activated transcription factor to regulate expression of the target genes
  • Null mutation in PgR gene leads to pleiotrophic reproductive abnormalities
  • Host Species: Mouse Clone: hPRa 2 + hPRa 3 Isotype: IgG1/κ + IgG1/κ Species Reactivity: Human, Horse, Sheep and Pig
  • Others not known
  • Epitope: N-terminal half of human PgR Immunogen: PgR from a human endometrial carcinoma (EnCa 101) grown in athymic mice Molecular Weight: 116kDa (B-form) and 81kDa (A-form) Positive Control: T47D or Breast CA Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunofluorescence Immunoprecipitation (Native and denatured) Sedimentation in Sucrose Gradient