46-205-182

CD205 Monoclonal Antibody (205yekta), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 46-205-182-Each-of-1 In Stock ₹ 39,605.00

46-205-182 - Each of 1

₹ 39,605.00

In Stock

Quantity

1

Base Price: ₹ 39,605.00

GST (18%): ₹ 7,128.90

Total Price: ₹ 46,733.90

Antigen

CD205

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q60767

Gene Symbols

LY75

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17076

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

205yekta

Conjugate

PerCP-eFluor 710

Gene

LY75

Gene Alias

CA-IX; CD205; CLEC13B; C-type lectin domain family 13 member B; DCL-1 fusion; DEC205; DEC-205; DEC-205/CD205 protein; gp200; gp200-MR6; group VI C-type animal lectin; LY75; ly-75; Lymphocyte antigen 75; membrane antigen MN; P54/58N; pMW1; RGD1565962; RP23-10L17.4

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • The 205yekta antibody reacts with mouse CD205, also known as DEC-205 (dendritic and epithelial cells, 205 kDa)
  • CD205 is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity
  • CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells
  • CD205 has been shown to bind to PE-Cy5.5 antibody and streptavidin conjugates; therefore, this format should not be used on CD205+ dendritic cells
  • CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity
  • CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells
  • CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region
  • Further, CD205 also prompts the reduced proliferation of B lymphocytes
  • Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.