Podoplanin Monoclonal Antibody (eBio8.1.1 (8.1.1)), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 46-538-182-Each-of-1 | In Stock | ₹ 36,668.00 |
46-538-182 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,668.00
GST (18%): ₹ 6,600.24
Total Price: ₹ 43,268.24
Antigen
Podoplanin
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q62011
Gene Symbols
PDPN
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14726
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
eBio8.1.1 (8.1.1)
Conjugate
PerCP-eFluor 710
Gene
PDPN
Gene Alias
29kDa cytosolic podoplanin intracellular domain; Aggrus; CTA-520D8.1; E11; E11 antigen epitope; epithelial cell surface transmembrane protein antigen; glycoprotein 36; Glycoprotein 38; glycoprotein, 36-KD; GP36; Gp38; GP40; HT1A-1; hT1alpha-1; hT1alpha-2; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); Ots8; OTS-8; OTTHUMP00000009640; OTTHUMP00000044504; PA2.26; PA2.26 antigen; PDPN; PICD; Podoplanin; PSEC0003; PSEC0025; pulmonary type I alveolar epithelial cell transmembrane differentiation marker; RANDAM-2; RP23-348F1.2; RTI140; RTI40; T1a; T1A2; T1A-2; T1alpha; T1-alpha; TI1A; Transmembrane glycoprotein E11; type I cell 40 kDa protein
Host Species
Syrian Hamster
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Podoplanin (PDPN, T1A, gp38, Aggrus) is a mucin type-1 glycoprotein with a 40-43 kDa molecular weight
- Podoplanin is expressed in many tumors and normal cells, especially lymphatic epithelial cells and follicular DCs
- Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells
- As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes
- Podoplanin appears to serve as a ligand for CLEC-2 and expression is positively correlated with tumors expressing greater invasive and metastatic potential
- Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue
- Further, it has also been determined that podoplanin expression is induced through Src activation of Cas and, recently, there are indications of podoplanin presence on Th17 cells
- Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC
- Dysfunction of the podoplanin protein has been linked to diseases such as lymphangioma and subglottis neoplasm
- Podoplanin has also been proposed as a marker for lung injury due to the physiological function of the protein.