RELM alpha Monoclonal Antibody (DS8RELM), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 46-544-180-Each-of-1 | In Stock | ₹ 17,088.00 |
46-544-180 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,088.00
GST (18%): ₹ 3,075.84
Total Price: ₹ 20,163.84
Antigen
RELM alpha
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9EP95
Gene Symbols
Retnla
Immunogen
Recombinant mouse RELM alpha protein
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
DS8RELM
Conjugate
PerCP-eFluor 710
Gene
Retnla
Gene Alias
1810019L16Rik; cysteine-rich secreted protein A12-gamma; Cysteine-rich secreted protein FIZZ1; Fizz1; Fizz-1; FIZZ2; found in inflammatory zone 1; Himf; HXCP2; Hypoxia-induced mitogenic factor; parasite-induced macrophage novel gene 1 protein; Pmng1; RELMa; RELMalpha; RELM-alpha; RELMb; RELMbeta; RELM-beta; resistin like alpha; resistin-like alpha; Retnla; Xcp2
Host Species
Rat
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
57262
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Related Products
Description
- Rat Monoclonal Antibody RELM alpha, also known as Resistin-like alpha or FIZZ1, is a small cytokine (88 aminoacids, MW 9.4 kDa) produced mostly by macrophages
- Its highest constitutive expression has been observed in small peritoneal macrophages, alveolar macrophages and adipose tissue macrophages
- It is strongly induced by IL-4 and IL-13
- Together with Arginase 1 and Ym-1, RELM alpha is considered one of the hallmarks of the M2 polarization of mouse macrophages, however, macrophages polarized with IL-10 (M2c) express neither RELM alpha nor Arginase 1
- Also, the expression patterns of RELM alpha and Arginase 1 in untreated tissue macrophages significantly differ
- Elevated levels of RELM alpha may indicate parasitic infection
- Humans do not have RELM alpha gene but human Resistin resembles mouse RELM alpha in respect to sequence, tissue distribution and function
- Other members of RELM family in mouse: RELM beta, RELM gamma and Resistin display different tissue distribution and functional properties
- RELM alpha plays an important role in parasite infection, mucosal inflammation and allergy.