4657682
HLA-DR Mouse anti-Human, Brilliant Violet 605, Clone: G46-6, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
HLA-DR
Applications
Flow Cytometry
Conjugate
Brilliant Violet 605
Regulatory Status
RUO
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Clone
G46-6
Classification
Monoclonal
Host Species
Mouse
Target Species
Baboon, Cynomolgus, Human, Rhesus Monkey
Isotype
IgG2a κ
Purification Method
Affinity Purified
Description
MHC class II antigen; HLA class II histocompatibility antigen
Related Products
Description
- The G46-6 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen
- HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6
- HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells: B cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells
- HLA-DR is also expressed on activated T cells
- This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells
- For optimal and reproducible results, BD Horizon Brilliant Stain Buffer should be used anytime two or more BD Horizon Brilliant dyes are used in the same experiment
- Fluorescent dye interactions may cause staining artifacts which may affect data interpretation
- The BD Horizon Brilliant Stain Buffer was designed to minimize these interactions
- More information can be found in the Technical Data Sheet of the BD Horizon Brilliant Stain Buffer (Cat
- No
- 563794).