47-587-482

CD357 (AITR/GITR) Monoclonal Antibody (DTA-1), APC-eFluor™ 780, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 47-587-482-Each-of-1 In Stock ₹ 36,401.00

47-587-482 - Each of 1

₹ 36,401.00

In Stock

Quantity

1

Base Price: ₹ 36,401.00

GST (18%): ₹ 6,552.18

Total Price: ₹ 42,953.18

Antigen

CD357 (AITR/GITR)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

O35714

Gene Symbols

Tnfrsf18

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21936

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

DTA-1

Conjugate

APC-eFluor 780

Gene

Tnfrsf18

Gene Alias

Activation-inducible TNFR family receptor; AITR; CD357; GITR; GITR-D; glucocorticoid-induced TNFR-related protein; PRO364; TNF receptor superfamily activation-inducible protein; TNF receptor superfamily member 18; TNFRSF18; Tumor necrosis factor receptor superfamily member 18; tumor necrosis factor receptor superfamily, member 18; UNQ319; UNQ319/PRO364

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2b κ

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Description

  • Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene
  • It is mapped to 1p36.33
  • This gene encodes a member of the TNF-receptor superfamily
  • The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+)CD4 (+) regulatory T cells
  • Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death
  • Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.