47370942
CD370 (Clec9A) Monoclonal Antibody (9A11), APC-eFluor™ 780, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 47370942-Each-of-1 | In Stock | ₹ 30,082.00 |
47370942 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,082.00
GST (18%): ₹ 5,414.76
Total Price: ₹ 35,496.76
Antigen
CD370 (Clec9A)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide
Gene Accession No.
Q6UXN8
Gene Symbols
CLEC9A
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
283420
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
9A11
Conjugate
APC-eFluor 780
Gene
CLEC9A
Gene Alias
9830005G06Rik; CD370; Clec9a; C-type lectin domain family 9 member A; C-type lectin domain family 9, member A; Dendritic cell natural killer lectin group receptor 1; DNGR1; DNGR-1; HEEE9341; RGD1562513; UNQ9341; UNQ9341/PRO34046
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- This monoclonal antibody 9A11 reacts with human CD370, also known as C-type lectin family member 9A (Clec9A) and DNGR1
- This type II transmembrane glycoprotein is present at the cell surface in the form of a homodimer
- CD370 is a cellular receptor expressed by myeloid cells that recognizes F-actin, a dead cell-associated antigen that is exposed in necrotic cells
- Upon ligation, CD370 recruits Syk kinase to the ITAM-like motif in its intracellular tail and facilitates endocytosis of antigenic material that is subsequently processed and cross-presented to CD8+ T cells
- Human CD370 is expressed by CD141+ (BDCA3+) dendritic cells and, to a lesser degree, by CD14+ CD16- monocytes
- Unlike in mice, human plasmacytoid dendritic cells do not express CD370
- This 9A11 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
- This can be used at 5 μL (0.125 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- APC-eFluor™ 780 emits at 780 nm and is excited with the Red laser (633 nm)
- Please make sure that your instrument is capable of detecting this fluorochrome
- Light sensitivity: This tandem dye is sensitive to photo-induced oxidation
- Please protect this vial and stained samples from light
- CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells.