48-150-282
CD150 Monoclonal Antibody (mShad150), eFluor™ 450, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 48-150-282-Each-of-1 | In Stock | ₹ 35,600.00 |
48-150-282 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,600.00
GST (18%): ₹ 6,408.00
Total Price: ₹ 42,008.00
Antigen
CD150
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9QUM4
Gene Symbols
Slamf1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
27218
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
mShad150
Conjugate
eFluor 450
Gene
Slamf1
Gene Alias
4933415F16; AA177906; CD150; CD150 antigen; CDw150; ESTM51; IPO-3; RGD1560634; signaling lymphocyte activation molecule; signaling lymphocytic activation molecule; signaling lymphocytic activation molecule family member 1; Slam; SLAM family member 1; Slamf1
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b λ
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Description
- CD150, designated SLAM (Signaling Lymphocyte Activation Molecule) or CDw150, belongs to the immunoglobulin gene superfamily and is involved in T cell stimulation
- SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation
- Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM
- It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells
- Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells
- CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation
- SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation
- Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM
- It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells
- Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells
- Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain
- Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).