4971483

Caspase-1 Antibody (14F468) - BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody has been used in 54 publications

Manufacturer: Fischer Scientific

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Antigen

Caspase-1

Concentration

1.0 mg/mL

Applications

Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Apoptosis, Caspases

Gene Accession No.

P29466

Gene ID (Entrez)

834

Immunogen

A synthetic peptide corresponding to amino acids 371-390 RKVRFSFEQPDGRAQMPTTE of human caspase-1 was used as immunogen.

Primary or Secondary

Primary

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Molecular Weight of Antigen

45 kDa

Clone

14F468

Dilution

Western Blot 0.5-2 ug/ml, Simple Western 1:50, Immunohistochemistry 1:100 - 1:500, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen reported in scientific literature (PMID 30930743)

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human, Mouse, Rat

Gene Alias

CASP-1, caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, caspase-1, EC 3.4.22, EC 3.4.22.36, ICEP45, IL-1 beta-converting enzyme, IL-1BC, IL1BC CASP1 nirs variant 1, IL1BCE, IL1B-convertase, interleukin 1-B converting enzyme, interleukin 1-beta convertase, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45

Gene Symbols

CASP1

Isotype

IgG1 κ

Purification Method

Protein G purified

Test Specificity

The antibody will recognize full-length Caspase-1 and cleaved caspase-1 forms that retain amino acids 371-390 of the Caspase-1 protein.

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Description

  • Caspase-1 Monoclonal specifically detects Caspase-1 in Human, Mouse, Rat samples
  • It is validated for Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.