50-075-942

CD75 Monoclonal Antibody (LN-1), eFluor™ 660, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-075-942-Each-of-1 In Stock ₹ 28,391.00

50-075-942 - Each of 1

₹ 28,391.00

In Stock

Quantity

1

Base Price: ₹ 28,391.00

GST (18%): ₹ 5,110.38

Total Price: ₹ 33,501.38

Antigen

CD75

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

P15907

Gene Symbols

ST6GAL1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6480

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

LN-1

Conjugate

eFluor 660

Gene

ST6GAL1

Gene Alias

Alpha 2,6-ST 1; AW742324; B-cell antigen CD75; beta galactoside alpha 2,6 sialyltransferase 1; beta-galactoside alpha-2,6-sialyltransferase 1; CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; Sialyltransferase 1; sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase); Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase); Sialyltransferase 1 (beta-galactoside alpha-26-sialytransferase); SIAT1; ST6 beta-galactosamide alpha-2,6-sialyltranferase 1; ST6 beta-galactoside alpha-2,6-sialyltransferase 1; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; St6gal; ST6Gal I; St6gal1; ST6GalI; St6Gal-I; ST6N

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgM

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Description

  • Description: This LN-1 monoclonal antibody reacts with human CD75, a cell surface carbohydrate determinant produced by alpha-2,6-sialytransferase
  • CD75 is expressed predominantly on mature B cells in peripheral blood and germinal centers, as well as several B cell lines (e.g., Raji, Ramos)
  • CD75 is also expressed on non-immune tissues such as breast, prostate, colon, liver, and kidney
  • Reports demonstrate that CD75 is a ligand of CD22
  • Studies have shown that, depending on fixation and tissue processing, the LN-1 antibody also recognizes astrocytes and microglia in the human brain
  • Applications Reported: This LN-1 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This LN-1 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
  • This can be used at 5 μL (0.25 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • eFluor™ 660 is a replacement for Alexa Fluor™ 647
  • eFluor™ 660 emits at 659 nm and is excited with the red laser (633 nm)
  • Please make sure that your instrument is capable of detecting this fluorochome
  • Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates
  • The encoded protein, which is normally found in the Golgi but which can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76
  • This protein is a member of glycosyltransferase family 29
  • Three transcript variants encoding two different isoforms have been found for this gene.