50-108-12
CD200 Monoclonal Antibody (OX90), PE, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-108-12-Each-of-1 | In Stock | ₹ 22,606.00 |
50-108-12 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,606.00
GST (18%): ₹ 4,069.08
Total Price: ₹ 26,675.08
Antigen
CD200
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
O54901
Gene Symbols
Cd200
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17470
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
OX90
Conjugate
PE
Gene
Cd200
Gene Alias
antigen identified by monoclonal antibody MRC OX-2; CD200; Cd200 antigen; Cd200 molecule; cell surface protein (thymocyte antigen identified by monoclonal antibody MRC-OX2); Cspmo2; hypothetical protein LOC534910; MOX1; MOX2; MRC; MRC OX-2 antigen; MRCOX2; My033; OX2; OX-2; OX-2 membrane glycoprotein
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The monoclonal antibody OX90.1 recognizes mouse CD200 also known as OX2
- CD200 is a member of the Ig superfamily with 2 Ig domains, a transmembrane and cytoplasmic domain
- CD200 is expressed on resting and activated B cells, a subset of resting and activated T cells, keratinocytes, peripheral and central nerve cells, follicular dendritic cells and ovarian cells
- The interaction with CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TN Falpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes
- Applications Reported: This OX90 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This OX90 antibody has been tested by flow cytometric analysis of mouse splenocytes
- This can be used at less than or equal to 0.25 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
- Filtration: 0.2 μm post-manufacturing filtered
- CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily
- CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation
- Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses
- Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues
- Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found
- Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.