ThPOK Monoclonal Antibody (2POK), PE, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-2355-Each-of-1 | In Stock | ₹ 34,265.00 |
50-112-2355 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,265.00
GST (18%): ₹ 6,167.70
Total Price: ₹ 40,432.70
Antigen
ThPOK
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q64321
Gene Symbols
Zbtb7b
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22724
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
2POK
Conjugate
PE
Gene
Zbtb7b
Gene Alias
CKROX; c-KROX; DKFZp686G01254; hcKROX; Krueppel-related zinc finger protein cKrox; RP11-307C12.9; T helper-inducing POZ/Krueppel factor; T-helper-inducing POZ/Krueppel-like factor; Thpok; Vzinc finger and BTB domain containing 7B; ZBTB15; ZBTB7B; ZFP67; Zfp-67; zinc finger and BTB domain containing 15; zinc finger and BTB domain containing 7B; Zinc finger and BTB domain-containing protein 15; Zinc finger and BTB domain-containing protein 7B; zinc finger protein 67; Zinc finger protein 67 homolog; zinc finger protein 857B; Zinc finger protein Th-POK; ZNF857B
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: This 2POK monoclonal antibody reacts with mouse ThPOK, which is also known as c-Krox and Zbtb7b
- In hematopoietic cells, this 78 kDa transcription factor is expressed in thymocytes and T lymphocytes in the spleen and lymph nodes
- In non-hematopoietic cells, ThPOK can be detected in the skin, heart, smooth muscle, and liver
- Studies demonstrate that ThPOK promotes CD4+ lineage differentiation by inhibiting the expression of CD8 lineage-specific genes such as Runx3
- ThPOK has also been shown to inhibit Cd4 silencing, another key facet required for differentiation to the CD4+ lineage
- In addition to its role in thymocyte development, ThPOK is involved in the effector functions of invariant natural killer T (iNKT) cells and gamma delta T cells
- Applications Reported: This 2POK antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This 2POK antibody has been tested by intracellular staining and flow cytometric analysis of mouse thymocytes using the Foxp3/Transcription Factor Staining Buffer Set (cat
- 00-5523) and protocol
- This can be used at less than or equal to 0.25 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes (e.g., COL1A1; MIM 120150) and has a role in development.