50-112-3100
CD201 (EPCR) Monoclonal Antibody (RCR-227), APC, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-3100-Each-of-1 | In Stock | ₹ 30,349.00 |
50-112-3100 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,349.00
GST (18%): ₹ 5,462.82
Total Price: ₹ 35,811.82
Antigen
CD201 (EPCR)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9UNN8
Gene Symbols
Procr
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10544
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
RCR-227
Conjugate
APC
Gene
Procr
Gene Alias
Activated protein C receptor; AI325044; APC receptor; bA42O4.2; CCCA; CCD41; CD antigen CD201; CD201; CD201 antigen; cell cycle, centrosome-associated protein; centrocyclin; Centrosomal protein CCD41; endothelial cell protein C receptor; Endothelial protein C receptor; Epcr; PROCR; protein C receptor; protein C receptor, endothelial
Host Species
Rat
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The monoclonal antibody RCR-227 reacts with human CD201, which is also known as the endothelial protein C receptor (EPCR), a 46-kDa transmembrane protein related to class I MHC
- CD201 was originally identified on vascular endothelium cells, predomitly larger blood vessels
- It is also expressed on monocytes, lymphocytes, hematopoietic stem cells, neutrophils, and eosinophils
- CD201 serves as a binding site for protein C, activated protein C (APC), and factor VII/VIIa
- A soluble form has also been identified in the plasma
- CD201 plays a role in controlling coagulation as disruption of its gene in mice caused placental thrombosis and early embryonic death
- This cell surface molecule is also involved in the anti-inflammatory response
- APC binding to CD201 enables PAR-1 activation that confers cytoprotective effects
- In monocytes, APC binding decreases secretion of proinflammatory cytokines, chemokines, and growth factors
- Finally, CD201 has been shown to inhibit lymphocyte migration
- Applications Reported: This RCR-227 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This RCR-227 antibody has been pre-titrated and tested by flow cytometric analysis of HUVECs
- This can be used at 5 μL (0.125 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- CD201 (EPCR) Monoclonal antibody specifically detects CD201 (EPCR) in Human samples
- It is validated for Flow Cytometry.