50-112-3121

CD317 (BST2, PDCA-1) Monoclonal Antibody (eBio129c (129c)), APC, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-3121-Each-of-1 In Stock ₹ 34,977.00

50-112-3121 - Each of 1

₹ 34,977.00

In Stock

Quantity

1

Base Price: ₹ 34,977.00

GST (18%): ₹ 6,295.86

Total Price: ₹ 41,272.86

Antigen

CD317 (BST2, PDCA-1)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q8R2Q8

Gene Symbols

Bst2

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

69550

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

eBio129c (129c)

Conjugate

APC

Gene

Bst2

Gene Alias

2310015I10Rik; bone marrow stromal antigen 2; bone marrow stromal cell antigen 2; Bst2; BST-2; C87040; CD317; Damp1; DAMP-1; DAMP-1 protein homolog; GREG; HM1.24 antigen; NPC-A-7; PDCA-1; protein DAMP-1; TETHERIN

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2b κ

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Description

  • Description: The eBio129c monoclonal antibody reacts with mouse PDCA-1 (BST2, CD317), a specific marker of plasmacytoid dendritic cells (pDC), also known as type I IFN-producing cells (IPC) in the naive mouse
  • Mouse IPCs are typically CD11c+, CD11b-, B220+, Ly-6C+, and CD62L+
  • PDCA-1 is predomitly expressed by IPCs in the naive mouse which represent sa very minor population (<0.5%) of splenocytes
  • It is upregulated on numerous cell types following stimulation which triggers an IFN response
  • PDCA-1 cycles between cell surface and intracellular compartments and may function to regulate trafficking of secreted cytokines
  • PDCA-1 (BST2) is the protein recognized by the antibody 120G8
  • The epitope recognized by eBio129c is distinct from eBio927; thus, the antibodies can be used to costain, purify and identify pDCs
  • Applications Reported: This eBio129c (129c) antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This eBio129c (129c) antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This can be used at less than or equal to 0.5 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • CD317 (BST2, PDCA-1) Monoclonal antibody specifically detects CD317 (BST2, PDCA-1) in Mouse samples
  • It is validated for Flow Cytometry.