50-112-3147
Siglec-G Monoclonal Antibody (SH2.1), APC, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-3147-Each-of-1 | In Stock | ₹ 40,406.00 |
50-112-3147 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,406.00
GST (18%): ₹ 7,273.08
Total Price: ₹ 47,679.08
Antigen
Siglec-G
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q80ZE3
Gene Symbols
Siglecg
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
243958
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
SH2.1
Conjugate
APC
Gene
Siglecg
Gene Alias
9830164H23; A630096C01Rik; mSiglec-G; sialic acid binding Ig-like lectin 10; sialic acid binding Ig-like lectin G; sialic acid-binding Ig-like lectin 10; Sialic acid-binding Ig-like lectin G; Siglec; Siglec 10; Siglec10; Siglec-10; Siglecg; Siglec-G
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- Description: The SH2.1 monoclonal antibody reacts with mouse siglec-G, which is also known as sialic acid-binding immunoglobulin-like lectin-G
- Siglec-G is an inhibitory receptor that is expressed in a B cell-specific manner with B1 B cells expressing the highest levels of siglec-G
- When overexpressed, siglec-G inhibits B cell receptor-mediated calcium signaling
- Siglec-G-deficient mice show a massive expansion of the B1a cell population as well as higher titers of natural IgM antibodies
- Siglec-G-deficient B1a cells show a lower level of spontaneous apoptosis and a prolonged life span, which may result from higher expression levels of the transcription factor NFATc1
- Siglec-G-dependent negative regulation exists in B1 cells, which may explain the naturally muted signaling response of B1 cells
- Applications Reported: This SH2.1 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This SH2.1 antibody has been tested by flow cytometric analysis of mouse splenocytes
- This can be used at less than or equal to 0.125 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser
- Filtration: 0
- Siglec-G Monoclonal antibody specifically detects Siglec-G in Mouse samples
- It is validated for Flow Cytometry.