CD369 (Clec7a, Dectin-1) Monoclonal Antibody (bg1fpj), PE-Cyanine7, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-3397-Each-of-1 | In Stock | ₹ 16,999.00 |
50-112-3397 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,999.00
GST (18%): ₹ 3,059.82
Total Price: ₹ 20,058.82
Antigen
CD369 (Clec7a, Dectin-1)
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q6QLQ4
Gene Symbols
Clec7a
Immunogen
Baculovirus-expressed Fc-containing protein
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
bg1fpj
Conjugate
PE-Cyanine7
Gene
Clec7a
Gene Alias
Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082
Host Species
Rat
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
56644
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
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Description
- Description: The monoclonal antibody bg1fpj recognizes mouse CD369, also known as Dectin-1 or CLEC7A, a type II transmembrane protein in the C-type lectin family
- The ligand is beta1, 3-glycan
- Beta glycans are a main component in polysaccharides and specifically beta1,3-linked carbohydrates are found in the cell wall of fungi, plants and some bacteria
- CD369 has been found to bind Candida, Aspergillis, Pneumocystis, Coccidioides and Mycobacterium
- Calcium dependent binding to ligand signals through syk via the ITAM domain in the cytoplasmic portion and results in endocyotosis/phagocytosis and production of cytokines (IL-2, IL-6, IL-10, TNF alpha, IL-1 beta, IL-23)
- A direct role in Th17 and Th1 differentiation has been attributed to CD369 signaling
- CD369 is expressed predomitly on myeloid cells (neutrophils, monocytes, macrophages, and dendritic cells)
- Low levels have also been reported on lymphocytes and mucosal epithelium
- Applications Reported: This bg1fpj antibody has been reported for use in flow cytometric analysis
- Applications Tested: This bg1fpj antibody has been tested by flow cytometric analysis of mouse lysed whole blood cells
- This can be used at less than or equal to 0.125 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- CD369 (Clec7a, Dectin-1) Monoclonal antibody specifically detects CD369 (Clec7a, Dectin-1) in Mouse samples
- It is validated for Flow Cytometry.