50-112-3474
CD284 (TLR4) Monoclonal Antibody (HTA125), PE-Cyanine7, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-3474-Each-of-1 | In Stock | ₹ 37,736.00 |
50-112-3474 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,736.00
GST (18%): ₹ 6,792.48
Total Price: ₹ 44,528.48
Antigen
CD284 (TLR4)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
O00206
Gene Symbols
TLR4
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7099
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
HTA125
Conjugate
PE-Cyanine7
Gene
TLR4
Gene Alias
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The HTA125 monoclonal antibody reacts with human Toll-like receptor 4 (TLR4)
- So far, at least ten members of the Toll family have been identified in humans
- This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor
- Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation
- TLR4 physically associates with another molecule called MD-2, and together with CD14, this complex is responsible for LPS recognition and signaling
- TLR4 is expressed by peripheral blood monocytes
- HTA125 has been reported to immunoprecipitate human TLR4 (∽100 kDa) from transfected cells
- Most TLR cell surface expression, especially TLR1 and TLR4, occurs at low levels on monocytes and at even lower levels on other cell types including granulocytes and immature dendritic cells (iDC)
- Furthermore, a relatively high degree of variability in TLR surface expression has been reported among normal donors
- Applications Reported: This HTA125 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This HTA125 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
- This can be used at 5 μL (1 μg) per test
- CD284 (TLR4) Monoclonal antibody specifically detects CD284 (TLR4) in Human samples
- It is validated for Flow Cytometry.