50-112-8897
CD105 (Endoglin) Monoclonal Antibody (MJ7/18), Biotin, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 50-112-8897-Each | In Stock | ₹ 7,533.85 |
50-112-8897 - Each
In Stock
Quantity
1
Base Price: ₹ 7,533.85
GST (18%): ₹ 1,356.093
Total Price: ₹ 8,889.943
Antigen
CD105 (Endoglin)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q63961
Gene Symbols
ENG
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13805
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
MJ7/18
Conjugate
Biotin
Gene
ENG
Gene Alias
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein
Host Species
Rat
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The MJ7/18 monoclonal antibody reacts with the mouse CD105 molecule, also known as Endoglin
- This 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells
- It is suggested that CD105 functions in adhesion and embryonic angiogenesis
- Applications Reported: The MJ7/18 antibody has been reported for use in flow cytometric analysis
- Applications Tested: The MJ7/18 antibody has been tested by flow cytometric analysis of bEnd.3 cells and mouse splenocytes
- This can be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Filtration: 0.2 μm post-manufacturing filtered
- CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells
- It exists on an O- and N-glycosylated homodimer
- Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker
- CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.