50-112-9339
IL-13 Monoclonal Antibody (eBio13A), PE-eFluor™ 610, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-112-9339-Each-of-1 | In Stock | ₹ 34,354.00 |
50-112-9339 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,354.00
GST (18%): ₹ 6,183.72
Total Price: ₹ 40,537.72
Antigen
IL-13
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P20109
Gene Symbols
Il13
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16163
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
eBio13A
Conjugate
PE-eFluor 610
Gene
Il13
Gene Alias
ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1 κ
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Description
- Description: The eBio13A antibody reacts with mouse IL-13
- IL-13 is a cytokine produced mainly by Th2 cells, but also by antigen-primed CD8 T cells
- IL-13 has a strong involvement in allergic inflammation and parasitic clearing
- In cancer models it has been shown to have either inhibitory or stimulatory activity depending on the tumor
- In humans, IL-13 is found to play a role in isotype switching in B cells
- IL-13 is implicating in down modulating macrophage activity, through the reduction of pro-inflammatory cytokines (IL-1, IL-6, IL-8, IL-10, IL-12) Applications Reported: This eBio13A antibody has been reported for use in intracellular staining followed by flow cytometric analysis
- Applications Tested: This eBio13A antibody has been tested by intracellular staining and flow cytometric analysis of Th2-polarized mouse splenocytes
- This can be used at less than or equal to 1 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- PE-eFluor™ 610 can be excited with laser lines from 488-561 nm and emits at 607 nm
- We recommend using a 610/20 band pass filter (equivalent to PE-Texas Red™)
- IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses
- IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils
- IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells
- Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF
- The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.