50-113-7058

CD51 Monoclonal Antibody (13C2), PE, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-113-7058-Each-of-1 In Stock ₹ 29,281.00

50-113-7058 - Each of 1

₹ 29,281.00

In Stock

Quantity

1

Base Price: ₹ 29,281.00

GST (18%): ₹ 5,270.58

Total Price: ₹ 34,551.58

Antigen

CD51

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with <0.1% sodium azide

Gene Accession No.

P06756, P80746

Gene Symbols

ITGAV

Immunogen

human CD51 from Cell suspension containing osteoclasts from osteoclastomas

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Human, Non-human Primate, Rabbit

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry

Clone

13C2

Conjugate

PE

Gene

ITGAV

Gene Alias

1110004F14Rik; 2610028E01Rik; alpha v integrin; antigen identified by monoclonal antibody L230; Cd51; CD61; D430040G12Rik; Dnmt3l-ps1 pseudogene; GP3A; GPIIIa; integrin alpha V; integrin alpha-V; Integrin alpha-V heavy chain; Integrin alpha-V light chain; integrin alphaVbeta3; integrin subunit alpha V; integrin, alpha V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); ITGAV; ITGB3; MSK8; Vitronectin receptor; vitronectin receptor alpha polypeptide (VNRA); vitronectin receptor subunit alpha; VNR; VNRA; VTNR

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

100008956, 281875, 3685

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • ITAGV encodes integrin alpha chain V
  • Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain
  • The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins
  • Among the known associating beta chains (beta chains 1,3,5,6, and 8, 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands, the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR)
  • In addition to adhesion, many integrins are known to facilitate signal transduction
  • The ITGB3 protein product is the integrin beta chain beta 3
  • Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain
  • A given chain may combine with multiple partners resulting in different integrins
  • Integrin beta 3 is found along with the alpha IIb chain in platelets
  • Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.