50-113-7072
CD1a Monoclonal Antibody (HI149), APC, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-113-7072-Each-of-1 | In Stock | ₹ 21,449.00 |
50-113-7072 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 21,449.00
GST (18%): ₹ 3,860.82
Total Price: ₹ 25,309.82
Antigen
CD1a
Classification
Monoclonal
Conjugate
APC
Gene
CD1A
Gene Alias
CD1; CD1 antigen; CD1.1; CD1A; CD1A antigen, a polypeptide; CD1a molecule; cd1a1; CD1A1 antigen; cluster of differentiation 1 A; cortical thymocyte antigen CD1A; differentiation antigen CD1-alpha-3; epidermal dendritic cell marker CD1a; FCB6; HTA1; hTa1 thymocyte antigen; R4; T6; T-cell surface antigen T6/Leu-6; T-cell surface glycoprotein CD1a
Host Species
Mouse
Purification Method
Size-exclusion chromatography
Regulatory Status
RUO
Gene ID (Entrez)
909
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry
Clone
HI149
Formulation
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.
P06126
Gene Symbols
CD1A
Immunogen
Human thymocytes
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
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Description
- CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta 2 microglobulin
- CD1a is expressed by cortical thymocytes, Langerhan's cells and by interdigitating cells
- CD1a is also expressed by some malignancies of T cell lineage and in histiocytosis X
- CD1a is expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues
- CD1a is structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin
- The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells
- The human genome contains five CD1 family genes organized in a cluster on chromosome 1
- The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands
- CD1a localizes to the plasma membrane and recycles vesicles of the early endocytic system
- At least five CD1 genes (CD1a, b, c, d, and e) are identified
- Alternatively spliced transcript variants of CD1a have been observed, but their biological validity have not been determined.