LAMP2 Monoclonal Antibody (ABL-93), FITC, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-113-7608-Each-of-1 | In Stock | ₹ 49,840.00 |
50-113-7608 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,840.00
GST (18%): ₹ 8,971.20
Total Price: ₹ 58,811.20
Antigen
LAMP2
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with <0.1% sodium azide
Gene Accession No.
P17047
Gene Symbols
LAMP2
Immunogen
Glycoproteins purified from BALB/c mouse embryo 3T3 cell line
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
ABL-93
Conjugate
FITC
Gene
LAMP2
Gene Alias
CD107 antigen-like family member B; CD107b; EGK_20887; Igp96; Lamp II; LAMP2; LAMP-2; LAMP-2 Isoform 2A; LAMP-2 Variant A; Lamp-2a; Lamp-2b; Lamp-2c; LAMPB; LGP110; LGP-110; LGP-96; LGP-B; lysosomal associated membrane protein 2; lysosomal membrane glycoprotein 2; lysosomal membrane glycoprotein type B; lysosomal-associated membrane protein 2; lysosome-associated membrane glycoprotein 2; lysosome-associated membrane protein 2; Mac3; RP23-193O17.2
Host Species
Rat
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
16784
Content And Storage
4° C, store in dark
Form
Liquid
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Description
- Description LAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins
- LAMP2 provides selectins with carbohydrate ligands, and may play a role in tumor cell metastasis, and have a function in the protection, maintenance, and adhesion of the lysosome
- Prior to posttranslational modification, LAMP2 is approximately 46 kDa polypeptide
- Mature, functional LAMP2 is extensively glycosylated with a variety of different N-linked and O-linked oligosaccharides with a total molecular weight of about 100-130 kDa
- LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail
- LAMP2 is used to monitor a very selective form of autophagy called chaperone-mediated autophagy
- LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail
- The LAMP protein has 3 variant forms: LAMP-2A, -2B, and 2C
- LAMP2, together with CD107a/LAMP-1, is a major constituent of lysosomal membrane
- The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes, and LAMP2 is an important regulator in successful phagosomal maturation
- LAMP2 deficiency causes an accumulation of autophagosomes in many tissues leading to cardiomyopathy and myopathy (Danon’s disease).