CD196 (CCR6) Monoclonal Antibody (R6H1), eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-129-60-Each-of-1 | In Stock | ₹ 11,303.00 |
50-129-60 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 11,303.00
GST (18%): ₹ 2,034.54
Total Price: ₹ 13,337.54
Antigen
CD196 (CCR6)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P51684
Gene Symbols
CCR6
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1235
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Immunoprecipitation, Western Blot
Clone
R6H1
Conjugate
Unconjugated
Gene
CCR6
Gene Alias
BN-1; CC chemokine receptor 6; C-C chemokine receptor type 6; C-C CKR-6; C-C motif chemokine receptor 6; CC-CKR-6; CCR6; CCR-6; CD196; chemokine (C-C motif) receptor 6; chemokine (C-C) receptor 6; chemokine receptor-like 3; CKR6; CKRL3; CKR-L3; Cmkbr6; DCR2; DRY6; DRY-6; G protein-coupled receptor 29; GPR29; GPRCY4; GPR-CY4; G-protein coupled receptor 29; KY411; LARC receptor; seven-transmembrane receptor, lymphocyte, 22; STRL22
Host Species
Mouse
Quantity
25 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
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Description
- Description: This R6H1 monoclonal antibody reacts with CD196 (also known as CCR6), a seven transmembrane G protein-coupled receptor expressed on T, B, dendritic, natural killer, and Langerhans cells
- This CC chemokine receptor uniquely binds MIP-3a/CCL20, a chemoattractant for dendritic cells, effector/memory T cells, and B cells
- CD196 is also involved in host defense and inflammation at epithelial sites
- Furthermore, this receptor has been implicated in Th17 differentiation and CD4+FoxP3+ regulatory T cell development
- Applications Reported: This R6H1 antibody has been reported for use in flow cytometric analysis, immunoblotting (WB), and immunoprecipitation
- Applications Tested: This R6H1 antibody has been tested by western blot on lysates prepared from normal human peripheral blood cells
- This antibody can be used at less than or equal to 5 μg/mL
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors
- The gene is preferentially expressed by immature dendritic cells and memory T cells
- The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha)
- This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses
- Alternatively spliced transcript variants that encode the same protein have been described for this gene.