50-137-64

Cytokeratin 7 Monoclonal Antibody (LP5K), eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each 50-137-64-Each In Stock ₹ 15,454.85

50-137-64 - Each

₹ 15,454.85

In Stock

Quantity

1

Base Price: ₹ 15,454.85

GST (18%): ₹ 2,781.873

Total Price: ₹ 18,236.723

Antigen

Cytokeratin 7

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P08729

Gene Symbols

KRT7

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3855

Content And Storage

4° C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Clone

LP5K

Conjugate

Unconjugated

Gene

KRT7

Gene Alias

CK7; CK-7; Cytokeratin 7; cytokeratin-7; D15Wsu77e; K2C7; K7; Kb7; keratin 7; keratin 7, type II; keratin associated protein 7.1; keratin complex 2, basic, gene 7; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; keratin, type II cytoskeletal 7; Keratin-7; keratin-associated protein 7-1; keratin-associated protein 7-1-like protein; Krt2-7; KRT7; krt7 {ECO:0000250; LOC100755511; LOC100861181; NACHT, LRR and PYD domains-containing protein 3; sarcolectin; SCL; si:ch73-233m11.1; si:ch73-233m11.2; similar to keratin 7; type II keratin Kb7; type II mesothelial keratin K7; type-II keratin Kb7; UniProtKB:P08729}

Host Species

Mouse

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • Description: This LP5K monoclonal antibody reacts with human cytokeratin 7 (K7), a 54-kDa type II (or basic) keratin expressed either alone or paired with cytokeratin 19 in simple epithelia, mesothelium, urothelium, and pseudostratified epithelium
  • Expression of cytokeratin 7 in the gastric foveolar, intestinal, and stratified squamous epithelia is extremely low or undetectable
  • Cytokeratins form the intracellular cytoskeletal network that maintains the integrity and stability of cells and tissues
  • In addition, most carcinomas express cytokeratin 7
  • The coordinated expression of this keratin with cytokeratin 20 is commonly used as a diagnostic marker for a variety of carcinomas
  • Applications Reported: This LP5K antibody has been reported for use in immunoblotting (WB) and immunocytochemistry (ICC)
  • Applications Tested: This LP5K antibody has been tested by immunofluorescent staining of paraformaldehyde fixed and permeabilized cells
  • This can be used at less than or equal to 10 μg/mL
  • It is recommended that the antibody be titrated for optimal performance in the assay of interest
  • Purity: Greater than 90%, as determined by SDS-PAGE
  • Aggregation: Less than 10%, as determined by HPLC
  • Filtration: 0.2 μm post-manufacturing filtered
  • Cytokeratin 7 blocks interferon-dependent interphase and stimulates DNA synthesis in cells
  • Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).