50-155-6876
TBK1 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-6876-Each-of-1 | In Stock | ₹ 43,546.81 |
50-155-6876 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,546.81
GST (18%): ₹ 7,838.426
Total Price: ₹ 51,385.236
Antigen
TBK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TBK1
Gene Alias
FLJ11330, NAK, T2K
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
29110, 56480
Content And Storage
4° C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
Q9UHD2, Q9WUN2
Gene Symbols
Tbk1
Immunogen
Between 675 and C-term
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
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Description
- The recommended shelf life for this product is 1 year from date of receipt
- Nuclear factor kappa B (NF-KB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses
- NF-KB mediates the expression of a great variety of genes in response to extracellular stimuli
- NF-KB is associated with IKB proteins in the cell cytoplasm, which inhibit NF-KB activity
- Phosphorylation of I-KB by IKB kinase (IKK) complex leads to degradation of I-KB and activation of NF-KB
- The IKK complex contains IKKa, IKKβ, and IKKK
- A novel IKK related kinase was recently identified and designated TBK1 (TANK-binding kinase 1), NAK (NF-KB-activating kinase), and T2K
- NAK/TBK1 activates IKKβ through direct phosphorylation
- NAK/TBK1 is activated by growth factors and PMA and mediates IKK and NF-kB activation in response to growth factors
- NAK/TBK1 functions upstream of NIK and the IKK complex
- NAK/TBK1 is also critical in protecting embryonic liver from apoptosis.