50-155-7607
Aurora B Polyclonal Antibody, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-7607-Each-of-1 | In Stock | ₹ 12,384.35 |
50-155-7607 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,384.35
GST (18%): ₹ 2,229.183
Total Price: ₹ 14,613.533
Antigen
Aurora B
Classification
Polyclonal
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
Q96GD4
Gene Symbols
AURKB
Immunogen
Between 300 and C-term
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Conjugate
Unconjugated
Gene
AURKB
Gene Alias
AIK1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9212
Content And Storage
4° C
Form
Liquid
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Aurora-B kinase (AurB) is a serine/threonine kinase which is the enzymatic core of the Chromosomal Passenger Complex (CPC)
- This complex functions in chromosome alignment and separation, histone modification, and cytokinesis
- CPC also includes three non-enzymatic subunits known as the inner centromere protein (INCENP), survivin, and borealin, which determine the activity, localization, stability, and possibly even the substrate specificity of AurB
- Two CPCs exist during mitosis: one containing all four members and another consisting of INCENP and AurB
- Quaternary CPC functions during chromosome alignment and cytokinesis, whereas the INCENP-AurB complex may be responsible for modifying histone H3
- AurB is overexpressed in a number of tumours, including primary breast and colon tumour samples
- Its expression in tumours seems to be linked with Aurora-A kinase, suggesting a feedback mechanism between the two proteins.