50-157-1623
USP28 Polyclonal Antibody, Bethyl Laboratories
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-157-1623-Each-of-1 | In Stock | ₹ 46,161.63 |
50-157-1623 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,161.63
GST (18%): ₹ 8,309.093
Total Price: ₹ 54,470.723
Antigen
USP28
Classification
Polyclonal
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
Q96RU2
Gene Symbols
USP28
Immunogen
Between 50 and 100
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry
Conjugate
Unconjugated
Gene
USP28
Gene Alias
Ubiquitin carboxyl-terminal hydrolase 28; Ubiquitin thiolesterase 28; Ubiquitin-specific processing protease 28; Deubiquitinating enzyme 28
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
57646
Content And Storage
4° C
Form
Liquid
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Dog, Rabbit, Orangutan, Monkey, Gorilla, Northern white-cheeked gibbon, Small-eared galago and Na Modification of target proteins by ubiquitin participates in a wide array of biological functions
- Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin
- However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity
- An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families
- Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes
- Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution
- USPs tend to release ubiquitin from a conjugated protein
- They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.