50-166-0092

TPMT Mouse anti-Canine, Human, Clone: OTI4C1, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-0092-Each-of-1 In Stock ₹ 60,342.00

50-166-0092 - Each of 1

₹ 60,342.00

In Stock

Quantity

1

Base Price: ₹ 60,342.00

GST (18%): ₹ 10,861.56

Total Price: ₹ 71,203.56

Antigen

TPMT

Classification

Monoclonal

Conjugate

Unconjugated

Gene

TPMT

Gene Alias

TPMTD

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

403536, 7172

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone

OTI4C1

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P51580, Q8HX86

Gene Symbols

TPMT

Immunogen

Full length human recombit protein of human TPMT produced in HEK293T cell.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Canine, Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine
  • Defects in TPMT are the cause of thiopurine S-methyltransferase deficiency (TPMT deficiency).TPMT is an enzyme involved in the normal metabolic inactivation of thiopurine drugs
  • These drugs are generally used as immunosupressants or cytotoxic drugs and are prescribed for a variety of clinical conditions including leukemia, autoimmune disease and organ transplantation
  • Patients with intermediate or no TPMT activity are at risk of toxicity after receiving standard doses of thiopurine drugs and it is shown that inter-individual differences in response to these drugs are largely determined by genetic variation at the TPMT locus.