50-166-8060

FOS Mouse anti-Human, Clone: OTI7D6, lyophilized, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-166-8060-Each-of-1 In Stock ₹ 60,342.00

50-166-8060 - Each of 1

₹ 60,342.00

In Stock

Quantity

1

Base Price: ₹ 60,342.00

GST (18%): ₹ 10,861.56

Total Price: ₹ 71,203.56

Antigen

FOS

Classification

Monoclonal

Conjugate

Unconjugated

Gene

FOS

Gene Alias

AP-1, C-FOS, p55

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2353

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin)

Clone

OTI7D6

Formulation

PBS with 8% trehalose and no preservative; pH 7.3

Gene Accession No.

P01100

Gene Symbols

FOS

Immunogen

Full length human recombit protein of human FOS produced in E.coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
  • 7KMWCO FBJ murine osteosarcoma viral oncogene homolog is commonly known as Cellular protooncogene Fos (c-Fos)
  • It belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14
  • c-Fos heterodimerizes with c-Jun to form the Activator Protein -1 (AP-1) transcription factor which regulates transcription of several genes that play an important role in cellular signal transduction, cell proliferation and differentiation
  • c-Fos has been shown to be phosphorylated by various stimuli including growth factors and insulin at atleast seven different sites
  • The best known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK which regulates localization of c-Fos to the nucleus and is thus important for c-Fos induced transcriptional activity.