50-166-8700
CDC42BPA Mouse anti-Human, Clone: OTI12C12, lyophilized, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-166-8700-Each-of-1 | In Stock | ₹ 60,342.00 |
50-166-8700 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 60,342.00
GST (18%): ₹ 10,861.56
Total Price: ₹ 71,203.56
Antigen
CDC42BPA
Classification
Monoclonal
Conjugate
Unconjugated
Gene
CDC42BPA
Gene Alias
MRCK, MRCKA, PK428
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8476
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Applications
Western Blot
Clone
OTI12C12
Formulation
PBS with 8% trehalose and no preservative; pH 7.3
Gene Accession No.
Q5VT25
Gene Symbols
CDC42BPA
Immunogen
Human recombit protein fragment corresponding to amino acids 1419-1638 of human CDC42BPA produced in E.coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No
- 7KMWCO MRCK alpha (myotonic dystrophy kinase-related Cdc42-binding kinase alpha) is a member of the dystrophia myotonica protein kinase (DMPK) family that functions downstream of Cdc42 in actin cytoskeletal reorganization
- It is a serine/threonine kinase with multiple functional domains, including phorbol ester-responsive C1 domain
- Three independent coiled-coil domains and the N-terminal region preceding the kinase domain are responsible for intermolecular interactions leading to MRCK alpha multimerization
- The transautophosphorylation process is critical for regulation of MRCK alpha catalytic activities
- Binding of phorbol esters to MRCK releases its autoinhibition, allowing N-terminal dimerization and subsequent kinase activation.