50-168-1978
CDC42BPA Monoclonal Antibody (OTI12C12), TrueMAB™, OriGene
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-168-1978-Each-of-1 | In Stock | ₹ 44,954.79 |
50-168-1978 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,954.79
GST (18%): ₹ 8,091.862
Total Price: ₹ 53,046.652
Antigen
CDC42BPA
Classification
Monoclonal
Conjugate
Unconjugated
Gene
CDC42BPA
Gene Alias
MRCK, MRCKA, PK428
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8476
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Clone
OTI12C12
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
Q5VT25
Gene Symbols
CDC42BPA
Immunogen
Human recombit protein fragment corresponding to amino acids 1419-1638 of human CDC42BPA produced in E.coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MRCK alpha (myotonic dystrophy kinase-related Cdc42-binding kinase alpha) is a member of the dystrophia myotonica protein kinase (DMPK) family that functions downstream of Cdc42 in actin cytoskeletal reorganization
- It is a serine/threonine kinase with multiple functional domains, including phorbol ester-responsive C1 domain
- Three independent coiled-coil domains and the N-terminal region preceding the kinase domain are responsible for intermolecular interactions leading to MRCK alpha multimerization
- The transautophosphorylation process is critical for regulation of MRCK alpha catalytic activities
- Binding of phorbol esters to MRCK releases its autoinhibition, allowing N-terminal dimerization and subsequent kinase activation.