50-167-5082

PSMB7 Mouse anti-Human, Mouse, Clone: OTI1E1, liquid, TrueMAB™

Manufacturer: OriGene

Select a Size

Pack Size SKU Availability Price
Each of 1 50-167-5082-Each-of-1 In Stock ₹ 20,470.00

50-167-5082 - Each of 1

₹ 20,470.00

In Stock

Quantity

1

Base Price: ₹ 20,470.00

GST (18%): ₹ 3,684.60

Total Price: ₹ 24,154.60

Antigen

PSMB7

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P70195, Q99436

Gene Symbols

PSMB7

Immunogen

Human recombit protein fragment corresponding to amino acids 58-277 of human PSMB7 produced in E.coli.

Quantity

30 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI1E1

Conjugate

Unconjugated

Gene

PSMB7

Gene Alias

Z

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19177, 5695

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure
  • The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits
  • Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway
  • An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides
  • This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome
  • Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit
  • This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).