50-167-6541
VHL Mouse anti-Human, Clone: OTI1E1, liquid, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-6541-Each-of-1 | In Stock | ₹ 20,470.00 |
50-167-6541 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 20,470.00
GST (18%): ₹ 3,684.60
Total Price: ₹ 24,154.60
Antigen
VHL
Classification
Monoclonal
Conjugate
Unconjugated
Gene
VHL
Gene Alias
HRCA1, RCA1, VHL1, pVHL
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7428
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI1E1
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.
P40337
Gene Symbols
VHL
Immunogen
Full length human recombit protein of human VHL produced in HEK293T cell.
Quantity
30 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Related Products
Description
- Von Hippel-Lindau syndrome (VHL) is a domitly inherited familial cancer syndrome predisposing to a variety of maligt and benign tumors
- A germline mutation of this gene is the basis of familial inheritance of VHL syndrome
- The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity
- This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen
- RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein
- Alternatively spliced transcript variants encoding distinct isoforms have been observed.