50-167-7126
SERPINA1 Mouse anti-Human, Clone: OTI11G2, liquid, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-7126-Each-of-1 | In Stock | ₹ 46,061.06 |
50-167-7126 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,061.06
GST (18%): ₹ 8,290.991
Total Price: ₹ 54,352.051
Antigen
SERPINA1
Classification
Monoclonal
Conjugate
Unconjugated
Gene
SERPINA1
Gene Alias
A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT, nNIF
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5265
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ELISA
Clone
OTI11G2
Formulation
PBS with <5% trehalose and 0.05% sodium azide
Gene Accession No.
P01009
Gene Symbols
SERPINA1
Immunogen
Protein expressed in 293T cell transfected with human SERPINA1 expression vector
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung
- In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma
- Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn
- Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation
- Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.