50-167-7196
PLK1 Mouse anti-Human, Clone: OTI8C12, liquid, TrueMAB™
Manufacturer: OriGene
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-167-7196-Each-of-1 | In Stock | ₹ 46,061.06 |
50-167-7196 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,061.06
GST (18%): ₹ 8,290.991
Total Price: ₹ 54,352.051
Antigen
PLK1
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with <5% trehalose and 0.05% sodium azide
Gene Accession No.
P53350
Gene Symbols
PLK1
Immunogen
Protein expressed in 293T cell transfected with human PLK1 expression vector
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA
Clone
OTI8C12
Conjugate
Unconjugated
Gene
PLK1
Gene Alias
PLK, STPK13
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5347
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
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Description
- PLK1 is a Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis
- Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains
- Phosphorylates BORA, BUB1B/BUBR1, CCNB1, CDC25C, CEP55, ECT2, ERCC6L, FBXO5/EMI1, FOXM1, KIF20A/MKLP2, CENPU, NEDD1, NINL, NPM1, NUDC, PKMYT1/MYT1, KIZ, PPP1R12A/MYPT1, PRC1, RACGAP1/CYK4, SGOL1, STAG2/SA2, TEX14, TOPORS, p73/TP73, TPT1 and WEE1
- Plays a key role in centrosome functions and the assembly of bipolar spindles by phosphorylating KIZ, NEDD1 and NINL.